ALung Technologies, Inc. - medical device company developing the world’s first commercial artificial lung device—the HemoLung. By delivering oxygen to the blood and removing carbon dioxide, the HemoLung provides safer and less expensive respiratory support than mechanical ventilation, the current standard of care.

AppCompTech (Applied Computationl Technologies) - software development company focused on a life sciences application in Radiation Treatment Planning for Cancer Therapy. The patented technology/software, called ProACTive™, shatters today’s industry-wide speed barrier to high accuracy dose calculation for radiation therapy. The blend of incredible speed with accuracy enables adaptive planning and creates a significant competitive advantage over existing treatment technology.

BIOSAFE  - produces innovative anti-microbial materials which globally impact the prevention of diseases and provide personal safety. BIOSAFE adds value to end products by providing long lasting microbial protection on the product surface. The proprietary anti-microbial is uniquely safe and effective.

Bridge Semiconductor Corporation - fab-less, mixed-signal semiconductor company developing a line of Application Specific Standard Products (ASSP) called Transanalog Interfaces™. Bridge’s initial market is thermal imaging. Bridge targets high worth, high margin applications where its products uniquely provide a lower price and/or higher performance.

Cardiorobotics  - medical device company focusing on unique Articulated Robotic MedProbes™, or robotic ARMs™, that need only a single point of entry into the body. These products are highly articulated access devices allowing minimally-invasive procedures to replace major surgical procedures for parts of the anatomy that are otherwise difficult to reach. The first products will have a small diameter and radius of curvature, along with unlimited degrees of freedom. These devices are teleoperated, steerable, visualization-enabled and provide a non-linear therapeutic path for delivering multiple tools to hard-to-reach locations.

Carmell - developing an exciting new concept in biomaterials: biologically-active plastics made from platelet-rich plasma, containing natural growth factors key for repairing injured tissue. Physical and degradation properties can be tailored to the application. Carmell is using these novel plastics in products designed to treat injuries to connective tissues (tendons, ligaments, cartilage), offering rapid healing and better outcomes.

Certes Networks (aka, CipherOptics) – developed patentable hardware/software that makes data-in-motion security simple whether securing data flows over your application environment or encrypting data-in-motion across global networks. CipherOptics’ unique approach to policy definition, key distribution and global encryption management provides unprecedented line rate performance across existing public and private Layer 2, 3 or 4 network infrastructures.

Columbia Northwest, Inc. - (LBO participation) – recreational vehicle manufacturer of light weight camping units; located in Mt. Pleasant, PA; growing 15% annually. 

DiaKine Therapeutics, Inc. –early clinical-stage pharmaceutical company using its platform technology to develop new, proprietary drugs for unmet medical needs in diabetes and complications related to diabetes. DiaKine Therapeutics’ primary focus is to develop new, proprietary therapies with the potential to dramatically change diabetes treatment by disrupting the inflammatory pathways that lead to the destruction of insulin-producing cells. Because of their unique anti-inflammatory and immune modulating properties, the drugs address type 1 and type 2 diabetes and many related complications.

Flashgroup - solves the information overload created by the explosion in size and coverage of the on-line social space.  Flashgroup solves this problem by providing each user with a prioritized personalized stream of information the user really cares about, using a unique real-time machine learning algorithm. Additionally, the user is offered personalized social spaces to discuss these topics, flashgroups, composed of small groups of people who currently share an interest and who are predicted to enjoy talking with each other.

FlyCast  - mobile broadcast network that aggregates entertainment content from a variety of existing sources and processes it for delivery to iPhone, BlackBerry, and Android-based cell phones.  FlyCast gives smartphone owners free access to nearly 1500 channels of music, weather, talk, and video, delivered wherever and whenever they choose.

INRange Management Systems, Inc. - tele-pharmacy fulfillment company whose flagship product, the INRange Telepharmacy Fulfillment System™, remotely monitors and manages drug therapy compliance in the patient’s domicile.  This product allows for bi-directional communications and provides the one element absent from current prescription drug therapy – pharmacist/clinician control over point of care medication delivery.

Intimate Bridge 2 Conception (IB2C) – created take-home conception aid technology designed to address the growing unmet need of delayed and/or unsuccessful natural fertility. IB2C is bridging the gap between natural intercourse and In-vitro fertilization (IVF) by optimizing a known approach in a new way - filling the existing void in conception within the privacy of the patient’s home.

medSage Technologies, LLC –web-based server solution providing a unique patient management system to the home medical equipment industry. medSage’s solution significantly drives revenues and profits from the existing business base while optimizing the revenue stream for new patients going forward.

PetsDx Veterinary Imaging, Inc. - seeks to become a leading provider of veterinary diagnostic imaging services. The $18 billion dollar overall veterinary market is growing at ~15% per year as owners demand better and more expensive care for their pets (e.g., hip replacements, chemotherapy, transplants, MRIs).

Lube Holdings, Inc. (Quaker, Steak, and Lube) - restaurant franchisor with unique concepts in design (NASCAR, motorcycle, speed/motor decor), food (16 unique sauces), and promotional events (All-You-Can-Eat specials, Bike nights, car shows, local community events) and whose unit sales ranked No. 5 in the top 30 Casual Dining Chain category in Q4 2003.

RedPath Integrated Pathology, Inc. - pathology services company integrating traditional pathology practice with molecular genetic analysis. Using its patented platform approach, Microdissection Genotyping™, they are leading the change from static to dynamic tissue analysis.

StageMark, Inc. –developed an early identification and monitoring solution for inflammatory diseases such as lupus. StageMark's platform CB-CAPs technology — for Cell-Bound Complement Activation Products — was discovered by Dr. Sue Manzi, MD, MPH and Joseph Ahearn, MD, Ph.D., rheumatology clinicians and scientists from the University of Pittsburgh Medical Center (UPMC) Lupus Center of Excellence at Magee Women’s Hospital.

STARR Life Sciences, Inc. - developed a cardiopulmonary platform technology for small animal-based medical research which led to the introduction of the MouseOx™, a pulse oximeter for mice and rats. STARR Life Sciences’ mission is to improve the efficacy of medical research by creating small-animal versions of human cardiopulmonary diagnostic and monitoring medical devices - ensuring that medical research results improve human health.

TalkShoe - is a social networking enabling technology. TalkShoe enables anyone to easily create, join or listen to “TalkCasts” -  group (voice) conversations, discussions, audio talk shows, live interactive podcasts, audio blogs, or monologues. TalkShoe looks for people who are interested, avid or passionate about a specific topic to host live Talkcasts … it’s voice on any telephones: regular phones, mobile phones, and/or computer phones (VoIP phones e.g. Skype) and a moderated Internet text chat as well - by topic. Think of it as connecting multiple friends or people by voice. TalkShoe has a massively scalable tier-one hardware telecommunications platform housed in a telco and is integrated over the Internet and down to each person’s desktop or telephone - providing free “consumer teleconferencing” service.

TowerCare Technologies, Inc. - growing software company utilizing a software-as-a-service (SaaS) model to expand the technically underserved and under-penetrated non-profit market. TowerCare developed a proprietary constituent-based architecture and built DonorPro using this architecture. It is a single software solution that manages donors, donations, fundraising, volunteers, employees, human resources, events, inventory, and more.

Voci Technologies, Inc – accelerate speech technologies for the benefit of consumers, businesses and national security.  Voci provides Automated Speech Recognition (ASR) on a unique hardware platform that delivers products to speech analytics providers to reduce their ASR annual operating costs by more than 80%. Voci is focused on two market segments - the ASR segment supporting speech analytics (call centers & national security), and transcription (medical & business) - and believes they have a $10B dollar market opportunity.

Vytrace, Inc (aka, Glucose Sensing Technologies)  - developing a highly accurate bedside monitor to monitor glucose at the bedside of critically ill patients in the Intensive Care Unit via a fiberoptic catheter with a photonic crystal sensor on the tip. This is not a consumer product for diabetic glucose monitoring. They also are exploring other analytes that may be monitored with sensor technology.

Wright Therapy Products  - provide safe, effective compression therapy for moderate to severe lymphedema and venous ulcers. Wrigth’s products treat underlying conditions by aiding return circulation through external compression -- highest pressures distally and less pressure in each chamber moving up the limb. These products have prevented amputations and healed long standing ulcers while allowing for safe, in home treatment.